At Ichnos Sciences, we’re working to make real progress in science and medicine. Explore our recent publications to discover how we’re shifting medicine forward. 

Date Title Lead Author Journal
11/04/2021 ISB 1442 ISB 1442, a First-in-Class CD38 and CD47 Bispecific Antibody Innate Cell Modulator for the Treatment of Relapsed Refractory Multiple Myeloma Sammicheli S. et al. American Society of Hematology Annual Meeting
05/03/2021 ISB 830 Telazorlimab in Atopic Dermatitis: Phase 2b Study Shows Improvement at 16 Weeks Sher, L. 2021 Society for Investigative Dermatology Virtual Meeting
01/28/2021 Cell Line Development Generation of homogeneous cell populations with tunable levels of transgene expression (PDF) Schlicht D. et al. Journal of Biotechnology
05/13/2020 BEAT® Antibody Engineering Platform A single mutation increases heavy-chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species Stutz C. et al. Journal of Biological Chemistry
09/12/2019 BEAT® Antibody Engineering Platform Single-step Protein A and Protein G avidity purification methods to support bispecific antibody discovery and development Ollier R. et al. mAbs
02/06/2019 ISB 830 GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis Guttman-Yassky E. et al. Journal of Allergy and Clinical Immunology
04/27/2017 BEAT® Antibody Engineering Platform Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies Skegro D. et al. Journal of Biological Chemistry

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Note: Assets that were previously identified as GBR XXXX are now identified as ISB XXXX.