Publications

At Ichnos Sciences, we’re working to make real progress in science and medicine. Explore our recent publications to discover how we’re shifting medicine forward. 

Date Title Lead Author Journal
11/04/2021 ISB 1442 ISB 1442, a First-in-Class CD38 and CD47 Bispecific Antibody Innate Cell Modulator for the Treatment of Relapsed Refractory Multiple Myeloma Sammicheli S. et al. American Society of Hematology Annual Meeting
05/03/2021 ISB 830 Telazorlimab in Atopic Dermatitis: Phase 2b Study Shows Improvement at 16 Weeks Sher, L. 2021 Society for Investigative Dermatology Virtual Meeting
01/28/2021 Cell Line Development Generation of homogeneous cell populations with tunable levels of transgene expression (PDF) Schlicht D. et al. Journal of Biotechnology
05/13/2020 BEAT® Antibody Engineering Platform A single mutation increases heavy-chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species Stutz C. et al. Journal of Biological Chemistry
09/12/2019 BEAT® Antibody Engineering Platform Single-step Protein A and Protein G avidity purification methods to support bispecific antibody discovery and development Ollier R. et al. mAbs
02/06/2019 ISB 830 GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis Guttman-Yassky E. et al. Journal of Allergy and Clinical Immunology
04/27/2017 BEAT® Antibody Engineering Platform Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies Skegro D. et al. Journal of Biological Chemistry

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Note: Assets that were previously identified as GBR XXXX are now identified as ISB XXXX.